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Page 1
Partitioning of cancer therapeutics in nuclear condensates.
Klein IA, Boija A, Afeyan LK, Hawken SW, Fan M, Dall'Agnese A, Oksuz O, Henninger JE, Shrinivas K, Sabari BR, Sagi I, Clark VE, Platt JM, Kar M, McCall PM, Zamudio AV, Manteiga JC, Coffey EL, Li CH, Hannett NM, Guo YE, Decker TM, Lee TI, Zhang T, Weng JK, Taatjes DJ, Chakraborty A, Sharp PA, Chang YT, Hyman AA, Gray NS, Young RA. Klein IA, et al. Among authors: hyman aa. Science. 2020 Jun 19;368(6497):1386-1392. doi: 10.1126/science.aaz4427. Science. 2020. PMID: 32554597 Free PMC article.
Visualizing the molecular sociology at the HeLa cell nuclear periphery.
Mahamid J, Pfeffer S, Schaffer M, Villa E, Danev R, Cuellar LK, Förster F, Hyman AA, Plitzko JM, Baumeister W. Mahamid J, et al. Among authors: hyman aa. Science. 2016 Feb 26;351(6276):969-72. doi: 10.1126/science.aad8857. Science. 2016. PMID: 26917770
RNA buffers the phase separation behavior of prion-like RNA binding proteins.
Maharana S, Wang J, Papadopoulos DK, Richter D, Pozniakovsky A, Poser I, Bickle M, Rizk S, Guillén-Boixet J, Franzmann TM, Jahnel M, Marrone L, Chang YT, Sterneckert J, Tomancak P, Hyman AA, Alberti S. Maharana S, et al. Among authors: hyman aa. Science. 2018 May 25;360(6391):918-921. doi: 10.1126/science.aar7366. Epub 2018 Apr 12. Science. 2018. PMID: 29650702 Free PMC article.
Phase separation provides a mechanism to reduce noise in cells.
Klosin A, Oltsch F, Harmon T, Honigmann A, Jülicher F, Hyman AA, Zechner C. Klosin A, et al. Among authors: hyman aa. Science. 2020 Jan 24;367(6476):464-468. doi: 10.1126/science.aav6691. Science. 2020. PMID: 31974256
Protein condensates as aging Maxwell fluids.
Jawerth L, Fischer-Friedrich E, Saha S, Wang J, Franzmann T, Zhang X, Sachweh J, Ruer M, Ijavi M, Saha S, Mahamid J, Hyman AA, Jülicher F. Jawerth L, et al. Among authors: hyman aa. Science. 2020 Dec 11;370(6522):1317-1323. doi: 10.1126/science.aaw4951. Science. 2020. PMID: 33303613
Phase-separating RNA-binding proteins form heterogeneous distributions of clusters in subsaturated solutions.
Kar M, Dar F, Welsh TJ, Vogel LT, Kühnemuth R, Majumdar A, Krainer G, Franzmann TM, Alberti S, Seidel CAM, Knowles TPJ, Hyman AA, Pappu RV. Kar M, et al. Among authors: hyman aa. Proc Natl Acad Sci U S A. 2022 Jul 12;119(28):e2202222119. doi: 10.1073/pnas.2202222119. Epub 2022 Jul 5. Proc Natl Acad Sci U S A. 2022. PMID: 35787038 Free PMC article.
CD-CODE: crowdsourcing condensate database and encyclopedia.
Rostam N, Ghosh S, Chow CFW, Hadarovich A, Landerer C, Ghosh R, Moon H, Hersemann L, Mitrea DM, Klein IA, Hyman AA, Toth-Petroczy A. Rostam N, et al. Among authors: hyman aa. Nat Methods. 2023 May;20(5):673-676. doi: 10.1038/s41592-023-01831-0. Epub 2023 Apr 6. Nat Methods. 2023. PMID: 37024650 Free PMC article.
298 results