Jiricny J - Search Results

1

Prime editing efficiency and fidelity are enhanced in the absence of mismatch repair.

Ferreira da Silva J, Oliveira GP, Arasa-Verge EA, Kagiou C, Moretton A, Timelthaler G, Jiricny J, Loizou JI. Ferreira da Silva J, et al. Among authors: jiricny j. Nat Commun. 2022 Feb 9;13(1):760. doi: 10.1038/s41467-022-28442-1. Nat Commun. 2022. PMID: 35140211 Free PMC article.

2

FAN1-MLH1 interaction affects repair of DNA interstrand cross-links and slipped-CAG/CTG repeats.

Porro A, Mohiuddin M, Zurfluh C, Spegg V, Dai J, Iehl F, Ropars V, Collotta G, Fishwick KM, Mozaffari NL, Guérois R, Jiricny J, Altmeyer M, Charbonnier JB, Pearson CE, Sartori AA. Porro A, et al. Among authors: jiricny j. Sci Adv. 2021 Jul 30;7(31):eabf7906. doi: 10.1126/sciadv.abf7906. Print 2021 Jul. Sci Adv. 2021. PMID: 34330701 Free PMC article.

3

FANCD2-Associated Nuclease 1 Partially Compensates for the Lack of Exonuclease 1 in Mismatch Repair.

Kratz K, Artola-Borán M, Kobayashi-Era S, Koh G, Oliveira G, Kobayashi S, Oliveira A, Zou X, Richter J, Tsuda M, Sasanuma H, Takeda S, Loizou JI, Sartori AA, Nik-Zainal S, Jiricny J. Kratz K, et al. Among authors: jiricny j. Mol Cell Biol. 2021 Aug 24;41(9):e0030321. doi: 10.1128/MCB.00303-21. Epub 2021 Aug 24. Mol Cell Biol. 2021. PMID: 34228493 Free PMC article.

4

A systematic CRISPR screen defines mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage.

Zou X, Koh GCC, Nanda AS, Degasperi A, Urgo K, Roumeliotis TI, Agu CA, Badja C, Momen S, Young J, Amarante TD, Side L, Brice G, Perez-Alonso V, Rueda D, Gomez C, Bushell W, Harris R, Choudhary JS; Genomics England Research Consortium; Jiricny J, Skarnes WC, Nik-Zainal S. Zou X, et al. Among authors: jiricny j. Nat Cancer. 2021 Jun;2(6):643-657. doi: 10.1038/s43018-021-00200-0. Epub 2021 Apr 26. Nat Cancer. 2021. PMID: 34164627 Free PMC article.

5

Transcription-coupled repair and mismatch repair contribute towards preserving genome integrity at mononucleotide repeat tracts.

Georgakopoulos-Soares I, Koh G, Momen SE, Jiricny J, Hemberg M, Nik-Zainal S. Georgakopoulos-Soares I, et al. Among authors: jiricny j. Nat Commun. 2020 Apr 24;11(1):1980. doi: 10.1038/s41467-020-15901-w. Nat Commun. 2020. PMID: 32332764 Free PMC article.

6

ATAD5 deficiency alters DNA damage metabolism and sensitizes cells to PARP inhibition.

Giovannini S, Weller MC, Hanzlíková H, Shiota T, Takeda S, Jiricny J. Giovannini S, et al. Among authors: jiricny j. Nucleic Acids Res. 2020 May 21;48(9):4928-4939. doi: 10.1093/nar/gkaa255. Nucleic Acids Res. 2020. PMID: 32297953 Free PMC article.

7

Ectopic Methylation of a Single Persistently Unmethylated CpG in the Promoter of the Vitellogenin Gene Abolishes Its Inducibility by Estrogen through Attenuation of Upstream Stimulating Factor Binding.

Kallenberger L, Erb R, Kralickova L, Patrignani A, Stöckli E, Jiricny J. Kallenberger L, et al. Among authors: jiricny j. Mol Cell Biol. 2019 Nov 12;39(23):e00436-19. doi: 10.1128/MCB.00436-19. Print 2019 Dec 1. Mol Cell Biol. 2019. PMID: 31548262 Free PMC article.

8

Synthetic lethality between BRCA1 deficiency and poly(ADP-ribose) polymerase inhibition is modulated by processing of endogenous oxidative DNA damage.

Giovannini S, Weller MC, Repmann S, Moch H, Jiricny J. Giovannini S, et al. Among authors: jiricny j. Nucleic Acids Res. 2019 Sep 26;47(17):9132-9143. doi: 10.1093/nar/gkz624. Nucleic Acids Res. 2019. PMID: 31329989 Free PMC article.

9

Author Correction: FAN1 interaction with ubiquitylated PCNA alleviates replication stress and preserves genomic integrity independently of BRCA2.

Porro A, Berti M, Pizzolato J, Bologna S, Kaden S, Saxer A, Ma Y, Nagasawa K, Sartori AA, Jiricny J. Porro A, et al. Among authors: jiricny j. Nat Commun. 2017 Dec 21;8(1):2285. doi: 10.1038/s41467-017-02130-x. Nat Commun. 2017. PMID: 29263317 Free PMC article.

10

FAN1 interaction with ubiquitylated PCNA alleviates replication stress and preserves genomic integrity independently of BRCA2.

Porro A, Berti M, Pizzolato J, Bologna S, Kaden S, Saxer A, Ma Y, Nagasawa K, Sartori AA, Jiricny J. Porro A, et al. Among authors: jiricny j. Nat Commun. 2017 Oct 20;8(1):1073. doi: 10.1038/s41467-017-01074-6. Nat Commun. 2017. PMID: 29051491 Free PMC article.

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