Lacor PN - Search Results

1

A glycine zipper motif mediates the formation of toxic β-amyloid oligomers in vitro and in vivo.

Fonte V, Dostal V, Roberts CM, Gonzales P, Lacor PN, Velasco PT, Magrane J, Dingwell N, Fan EY, Silverman MA, Stein GH, Link CD. Fonte V, et al. Among authors: lacor pn. Mol Neurodegener. 2011 Aug 23;6(1):61. doi: 10.1186/1750-1326-6-61. Mol Neurodegener. 2011. PMID: 21861874 Free PMC article.

2

A glycine zipper motif mediates the formation of toxic β-amyloid oligomers in vitro and in vivo.

Fonte V, Dostal V, Roberts CM, Gonzales P, Lacor PN, Velasco PT, Magrane J, Dingwell N, Fan EY, Silverman MA, Stein GH, Link CD. Fonte V, et al. Among authors: lacor pn. Mol Neurodegener. 2011 Aug 23;6(1):61. doi: 10.1186/1750-1326-6-61. Mol Neurodegener. 2011. PMID: 21861874 Free PMC article.

3

Deleterious effects of amyloid beta oligomers acting as an extracellular scaffold for mGluR5.

Renner M, Lacor PN, Velasco PT, Xu J, Contractor A, Klein WL, Triller A. Renner M, et al. Among authors: lacor pn. Neuron. 2010 Jun 10;66(5):739-54. doi: 10.1016/j.neuron.2010.04.029. Neuron. 2010. PMID: 20547131 Free PMC article.

4

Synaptic targeting by Alzheimer's-related amyloid beta oligomers.

Lacor PN, Buniel MC, Chang L, Fernandez SJ, Gong Y, Viola KL, Lambert MP, Velasco PT, Bigio EH, Finch CE, Krafft GA, Klein WL. Lacor PN, et al. J Neurosci. 2004 Nov 10;24(45):10191-200. doi: 10.1523/JNEUROSCI.3432-04.2004. J Neurosci. 2004. PMID: 15537891 Free PMC article.

5

Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease.

Lacor PN, Buniel MC, Furlow PW, Clemente AS, Velasco PT, Wood M, Viola KL, Klein WL. Lacor PN, et al. J Neurosci. 2007 Jan 24;27(4):796-807. doi: 10.1523/JNEUROSCI.3501-06.2007. J Neurosci. 2007. PMID: 17251419 Free PMC article.

6

Alzheimer's-associated Abeta oligomers show altered structure, immunoreactivity and synaptotoxicity with low doses of oleocanthal.

Pitt J, Roth W, Lacor P, Smith AB 3rd, Blankenship M, Velasco P, De Felice F, Breslin P, Klein WL. Pitt J, et al. Toxicol Appl Pharmacol. 2009 Oct 15;240(2):189-97. doi: 10.1016/j.taap.2009.07.018. Epub 2009 Jul 23. Toxicol Appl Pharmacol. 2009. PMID: 19631677 Free PMC article.

7

Synapse-binding subpopulations of Aβ oligomers sensitive to peptide assembly blockers and scFv antibodies.

Velasco PT, Heffern MC, Sebollela A, Popova IA, Lacor PN, Lee KB, Sun X, Tiano BN, Viola KL, Eckermann AL, Meade TJ, Klein WL. Velasco PT, et al. Among authors: lacor pn. ACS Chem Neurosci. 2012 Nov 21;3(11):972-81. doi: 10.1021/cn300122k. Epub 2012 Oct 23. ACS Chem Neurosci. 2012. PMID: 23173076 Free PMC article.

8

Alzheimer's disease-type neuronal tau hyperphosphorylation induced by A beta oligomers.

De Felice FG, Wu D, Lambert MP, Fernandez SJ, Velasco PT, Lacor PN, Bigio EH, Jerecic J, Acton PJ, Shughrue PJ, Chen-Dodson E, Kinney GG, Klein WL. De Felice FG, et al. Among authors: lacor pn. Neurobiol Aging. 2008 Sep;29(9):1334-47. doi: 10.1016/j.neurobiolaging.2007.02.029. Epub 2007 Apr 2. Neurobiol Aging. 2008. PMID: 17403556 Free PMC article.

9

A human scFv antibody that targets and neutralizes high molecular weight pathogenic amyloid-β oligomers.

Sebollela A, Cline EN, Popova I, Luo K, Sun X, Ahn J, Barcelos MA, Bezerra VN, Lyra E Silva NM, Patel J, Pinheiro NR, Qin LA, Kamel JM, Weng A, DiNunno N, Bebenek AM, Velasco PT, Viola KL, Lacor PN, Ferreira ST, Klein WL. Sebollela A, et al. Among authors: lacor pn. J Neurochem. 2017 Sep;142(6):934-947. doi: 10.1111/jnc.14118. Epub 2017 Aug 2. J Neurochem. 2017. PMID: 28670737 Free PMC article.

10

Brain transit and ameliorative effects of intranasally delivered anti-amyloid-β oligomer antibody in 5XFAD mice.

Xiao C, Davis FJ, Chauhan BC, Viola KL, Lacor PN, Velasco PT, Klein WL, Chauhan NB. Xiao C, et al. Among authors: lacor pn. J Alzheimers Dis. 2013;35(4):777-88. doi: 10.3233/JAD-122419. J Alzheimers Dis. 2013. PMID: 23542865 Free PMC article.

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