Leidel SA - Search Results

1

PDCD4 controls the G1/S-phase transition in a telomerase-immortalized epithelial cell line and affects the expression level and translation of multiple mRNAs.

Haas A, Nilges BS, Leidel SA, Klempnauer KH. Haas A, et al. Among authors: leidel sa. Sci Rep. 2020 Feb 17;10(1):2758. doi: 10.1038/s41598-020-59678-w. Sci Rep. 2020. PMID: 32066800 Free PMC article.

2

Dual randomization of oligonucleotides to reduce the bias in ribosome-profiling libraries.

Lecanda A, Nilges BS, Sharma P, Nedialkova DD, Schwarz J, Vaquerizas JM, Leidel SA. Lecanda A, et al. Among authors: leidel sa. Methods. 2016 Sep 1;107:89-97. doi: 10.1016/j.ymeth.2016.07.011. Epub 2016 Jul 19. Methods. 2016. PMID: 27450428 Free PMC article.

3

The novel lysine specific methyltransferase METTL21B affects mRNA translation through inducible and dynamic methylation of Lys-165 in human eukaryotic elongation factor 1 alpha (eEF1A).

Malecki J, Aileni VK, Ho AYY, Schwarz J, Moen A, Sørensen V, Nilges BS, Jakobsson ME, Leidel SA, Falnes PØ. Malecki J, et al. Among authors: leidel sa. Nucleic Acids Res. 2017 May 5;45(8):4370-4389. doi: 10.1093/nar/gkx002. Nucleic Acids Res. 2017. PMID: 28108655 Free PMC article.

4

Methylation of human eukaryotic elongation factor alpha (eEF1A) by a member of a novel protein lysine methyltransferase family modulates mRNA translation.

Jakobsson ME, Malecki J, Nilges BS, Moen A, Leidel SA, Falnes PØ. Jakobsson ME, et al. Among authors: leidel sa. Nucleic Acids Res. 2017 Aug 21;45(14):8239-8254. doi: 10.1093/nar/gkx432. Nucleic Acids Res. 2017. PMID: 28520920 Free PMC article.

5

Enzymatic or In Vivo Installation of Propargyl Groups in Combination with Click Chemistry for the Enrichment and Detection of Methyltransferase Target Sites in RNA.

Hartstock K, Nilges BS, Ovcharenko A, Cornelissen NV, Püllen N, Lawrence-Dörner AM, Leidel SA, Rentmeister A. Hartstock K, et al. Among authors: leidel sa. Angew Chem Int Ed Engl. 2018 May 22;57(21):6342-6346. doi: 10.1002/anie.201800188. Epub 2018 Mar 22. Angew Chem Int Ed Engl. 2018. PMID: 29461645

6

The dual methyltransferase METTL13 targets N terminus and Lys55 of eEF1A and modulates codon-specific translation rates.

Jakobsson ME, Małecki JM, Halabelian L, Nilges BS, Pinto R, Kudithipudi S, Munk S, Davydova E, Zuhairi FR, Arrowsmith CH, Jeltsch A, Leidel SA, Olsen JV, Falnes PØ. Jakobsson ME, et al. Among authors: leidel sa. Nat Commun. 2018 Aug 24;9(1):3411. doi: 10.1038/s41467-018-05646-y. Nat Commun. 2018. PMID: 30143613 Free PMC article.

7

Humans and other commonly used model organisms are resistant to cycloheximide-mediated biases in ribosome profiling experiments.

Sharma P, Wu J, Nilges BS, Leidel SA. Sharma P, et al. Among authors: leidel sa. Nat Commun. 2021 Aug 24;12(1):5094. doi: 10.1038/s41467-021-25411-y. Nat Commun. 2021. PMID: 34429433 Free PMC article.

8

Analysis of codon-specific translation by ribosome profiling.

Kim Y, Eggers C, Shvetsova E, Kleemann L, Sin O, Leidel SA. Kim Y, et al. Among authors: leidel sa. Methods Enzymol. 2021;658:191-223. doi: 10.1016/bs.mie.2021.06.025. Epub 2021 Aug 23. Methods Enzymol. 2021. PMID: 34517947

9

Differential Requirement for Translation Initiation Factor Pathways during Ecdysone-Dependent Neuronal Remodeling in Drosophila.

Rode S, Ohm H, Anhäuser L, Wagner M, Rosing M, Deng X, Sin O, Leidel SA, Storkebaum E, Rentmeister A, Zhu S, Rumpf S. Rode S, et al. Among authors: leidel sa. Cell Rep. 2018 Aug 28;24(9):2287-2299.e4. doi: 10.1016/j.celrep.2018.07.074. Cell Rep. 2018. PMID: 30157424 Free article.

10

The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins.

Blasco-Moreno B, de Campos-Mata L, Böttcher R, García-Martínez J, Jungfleisch J, Nedialkova DD, Chattopadhyay S, Gas ME, Oliva B, Pérez-Ortín JE, Leidel SA, Choder M, Díez J. Blasco-Moreno B, et al. Among authors: leidel sa. Nat Commun. 2019 Mar 21;10(1):1298. doi: 10.1038/s41467-019-09199-6. Nat Commun. 2019. PMID: 30899024 Free PMC article.

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