Levens D - Search Results

1

NMR-driven discovery of benzoylanthranilic acid inhibitors of far upstream element binding protein binding to the human oncogene c-myc promoter.

Huth JR, Yu L, Collins I, Mack J, Mendoza R, Isaac B, Braddock DT, Muchmore SW, Comess KM, Fesik SW, Clore GM, Levens D, Hajduk PJ. Huth JR, et al. Among authors: levens d. J Med Chem. 2004 Sep 23;47(20):4851-7. doi: 10.1021/jm0497803. J Med Chem. 2004. PMID: 15369388

2

Structure and dynamics of KH domains from FBP bound to single-stranded DNA.

Braddock DT, Louis JM, Baber JL, Levens D, Clore GM. Braddock DT, et al. Among authors: levens d. Nature. 2002 Feb 28;415(6875):1051-6. doi: 10.1038/4151051a. Nature. 2002. PMID: 11875576

3

Molecular basis of sequence-specific single-stranded DNA recognition by KH domains: solution structure of a complex between hnRNP K KH3 and single-stranded DNA.

Braddock DT, Baber JL, Levens D, Clore GM. Braddock DT, et al. Among authors: levens d. EMBO J. 2002 Jul 1;21(13):3476-85. doi: 10.1093/emboj/cdf352. EMBO J. 2002. PMID: 12093748 Free PMC article.

4

TFIIH operates through an expanded proximal promoter to fine-tune c-myc expression.

Weber A, Liu J, Collins I, Levens D. Weber A, et al. Among authors: levens d. Mol Cell Biol. 2005 Jan;25(1):147-61. doi: 10.1128/MCB.25.1.147-161.2005. Mol Cell Biol. 2005. PMID: 15601838 Free PMC article.

5

Dimerization of FIR upon FUSE DNA binding suggests a mechanism of c-myc inhibition.

Crichlow GV, Zhou H, Hsiao HH, Frederick KB, Debrosse M, Yang Y, Folta-Stogniew EJ, Chung HJ, Fan C, De la Cruz EM, Levens D, Lolis E, Braddock D. Crichlow GV, et al. Among authors: levens d. EMBO J. 2008 Jan 9;27(1):277-89. doi: 10.1038/sj.emboj.7601936. Epub 2007 Dec 6. EMBO J. 2008. PMID: 18059478 Free PMC article.

6

Loss of FBP function arrests cellular proliferation and extinguishes c-myc expression.

He L, Liu J, Collins I, Sanford S, O'Connell B, Benham CJ, Levens D. He L, et al. Among authors: levens d. EMBO J. 2000 Mar 1;19(5):1034-44. doi: 10.1093/emboj/19.5.1034. EMBO J. 2000. PMID: 10698944 Free PMC article.

7

Transcriptional consequences of topoisomerase inhibition.

Collins I, Weber A, Levens D. Collins I, et al. Among authors: levens d. Mol Cell Biol. 2001 Dec;21(24):8437-51. doi: 10.1128/MCB.21.24.8437-8451.2001. Mol Cell Biol. 2001. PMID: 11713279 Free PMC article.

8

A unique transactivation sequence motif is found in the carboxyl-terminal domain of the single-strand-binding protein FBP.

Duncan R, Collins I, Tomonaga T, Zhang T, Levens D. Duncan R, et al. Among authors: levens d. Mol Cell Biol. 1996 May;16(5):2274-82. doi: 10.1128/MCB.16.5.2274. Mol Cell Biol. 1996. PMID: 8628294 Free PMC article.

9

The FBP interacting repressor targets TFIIH to inhibit activated transcription.

Liu J, He L, Collins I, Ge H, Libutti D, Li J, Egly JM, Levens D. Liu J, et al. Among authors: levens d. Mol Cell. 2000 Feb;5(2):331-41. doi: 10.1016/s1097-2765(00)80428-1. Mol Cell. 2000. PMID: 10882074 Free article.

10

Cellular nucleic acid binding protein regulates the CT element of the human c-myc protooncogene.

Michelotti EF, Tomonaga T, Krutzsch H, Levens D. Michelotti EF, et al. Among authors: levens d. J Biol Chem. 1995 Apr 21;270(16):9494-9. doi: 10.1074/jbc.270.16.9494. J Biol Chem. 1995. PMID: 7721877 Free article.

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