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Structure of the Plasmodium 6-cysteine s48/45 domain.
Arredondo SA, Cai M, Takayama Y, MacDonald NJ, Anderson DE, Aravind L, Clore GM, Miller LH. Arredondo SA, et al. Among authors: macdonald nj. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6692-7. doi: 10.1073/pnas.1204363109. Epub 2012 Apr 9. Proc Natl Acad Sci U S A. 2012. PMID: 22493233 Free PMC article.
Phase 1 study of two merozoite surface protein 1 (MSP1(42)) vaccines for Plasmodium falciparum malaria.
Malkin E, Long CA, Stowers AW, Zou L, Singh S, MacDonald NJ, Narum DL, Miles AP, Orcutt AC, Muratova O, Moretz SE, Zhou H, Diouf A, Fay M, Tierney E, Leese P, Mahanty S, Miller LH, Saul A, Martin LB. Malkin E, et al. Among authors: macdonald nj. PLoS Clin Trials. 2007;2(4):e12. doi: 10.1371/journal.pctr.0020012. Epub 2007 Apr 6. PLoS Clin Trials. 2007. PMID: 17415408 Free PMC article.
Characterization of a protective Escherichia coli-expressed Plasmodium falciparum merozoite surface protein 3 indicates a non-linear, multi-domain structure.
Tsai CW, Duggan PF, Jin AJ, Macdonald NJ, Kotova S, Lebowitz J, Hurt DE, Shimp RL Jr, Lambert L, Miller LH, Long CA, Saul A, Narum DL. Tsai CW, et al. Among authors: macdonald nj. Mol Biochem Parasitol. 2009 Mar;164(1):45-56. doi: 10.1016/j.molbiopara.2008.11.006. Epub 2008 Nov 27. Mol Biochem Parasitol. 2009. PMID: 19073223 Free PMC article.
Structure of the Plasmodium falciparum circumsporozoite protein, a leading malaria vaccine candidate.
Plassmeyer ML, Reiter K, Shimp RL Jr, Kotova S, Smith PD, Hurt DE, House B, Zou X, Zhang Y, Hickman M, Uchime O, Herrera R, Nguyen V, Glen J, Lebowitz J, Jin AJ, Miller LH, MacDonald NJ, Wu Y, Narum DL. Plassmeyer ML, et al. Among authors: macdonald nj. J Biol Chem. 2009 Sep 25;284(39):26951-63. doi: 10.1074/jbc.M109.013706. Epub 2009 Jul 24. J Biol Chem. 2009. PMID: 19633296 Free PMC article.
Identification of VAR2CSA domain-specific inhibitory antibodies of the Plasmodium falciparum erythrocyte membrane protein 1 using a novel flow cytometry assay.
Obiakor H, Avril M, Macdonald NJ, Srinivasan P, Reiter K, Anderson C, Holmes KL, Fried M, Duffy PE, Smith JD, Narum DL, Miller LH. Obiakor H, et al. Among authors: macdonald nj. Clin Vaccine Immunol. 2013 Mar;20(3):433-42. doi: 10.1128/CVI.00638-12. Epub 2013 Jan 23. Clin Vaccine Immunol. 2013. PMID: 23345587 Free PMC article.
Reversible Conformational Change in the Plasmodium falciparum Circumsporozoite Protein Masks Its Adhesion Domains.
Herrera R, Anderson C, Kumar K, Molina-Cruz A, Nguyen V, Burkhardt M, Reiter K, Shimp R Jr, Howard RF, Srinivasan P, Nold MJ, Ragheb D, Shi L, DeCotiis M, Aebig J, Lambert L, Rausch KM, Muratova O, Jin A, Reed SG, Sinnis P, Barillas-Mury C, Duffy PE, MacDonald NJ, Narum DL. Herrera R, et al. Among authors: macdonald nj. Infect Immun. 2015 Oct;83(10):3771-80. doi: 10.1128/IAI.02676-14. Epub 2015 Jul 13. Infect Immun. 2015. PMID: 26169272 Free PMC article.
Structural and Immunological Characterization of Recombinant 6-Cysteine Domains of the Plasmodium falciparum Sexual Stage Protein Pfs230.
MacDonald NJ, Nguyen V, Shimp R, Reiter K, Herrera R, Burkhardt M, Muratova O, Kumar K, Aebig J, Rausch K, Lambert L, Dawson N, Sattabongkot J, Ambroggio X, Duffy PE, Wu Y, Narum DL. MacDonald NJ, et al. J Biol Chem. 2016 Sep 16;291(38):19913-22. doi: 10.1074/jbc.M116.732305. Epub 2016 Jul 18. J Biol Chem. 2016. PMID: 27432885 Free PMC article.
83 results