Merkl R - Search Results

1

The Alazami Syndrome-Associated Protein LARP7 Guides U6 Small Nuclear RNA Modification and Contributes to Splicing Robustness.

Hasler D, Meduri R, Bąk M, Lehmann G, Heizinger L, Wang X, Li ZT, Sement FM, Bruckmann A, Dock-Bregeon AC, Merkl R, Kalb R, Grauer E, Kunstmann E, Zavolan M, Liu MF, Fischer U, Meister G. Hasler D, et al. Among authors: merkl r. Mol Cell. 2020 Mar 5;77(5):1014-1031.e13. doi: 10.1016/j.molcel.2020.01.001. Epub 2020 Feb 3. Mol Cell. 2020. PMID: 32017898 Free article.

2

Evidence for the preferential reuse of sub-domain motifs in primordial protein folds.

Heizinger L, Merkl R. Heizinger L, et al. Among authors: merkl r. Proteins. 2021 Sep;89(9):1167-1179. doi: 10.1002/prot.26089. Epub 2021 May 14. Proteins. 2021. PMID: 33957009

3

The Arabidopsis THO/TREX component TEX1 functionally interacts with MOS11 and modulates mRNA export and alternative splicing events.

Sørensen BB, Ehrnsberger HF, Esposito S, Pfab A, Bruckmann A, Hauptmann J, Meister G, Merkl R, Schubert T, Längst G, Melzer M, Grasser M, Grasser KD. Sørensen BB, et al. Among authors: merkl r. Plant Mol Biol. 2017 Feb;93(3):283-298. doi: 10.1007/s11103-016-0561-9. Epub 2016 Dec 21. Plant Mol Biol. 2017. PMID: 28004241

4

The Adaptor Protein ENY2 Is a Component of the Deubiquitination Module of the Arabidopsis SAGA Transcriptional Co-activator Complex but not of the TREX-2 Complex.

Pfab A, Bruckmann A, Nazet J, Merkl R, Grasser KD. Pfab A, et al. Among authors: merkl r. J Mol Biol. 2018 May 11;430(10):1479-1494. doi: 10.1016/j.jmb.2018.03.018. Epub 2018 Mar 26. J Mol Biol. 2018. PMID: 29588169

5

Generation of catalytic human Ago4 identifies structural elements important for RNA cleavage.

Hauptmann J, Kater L, Löffler P, Merkl R, Meister G. Hauptmann J, et al. Among authors: merkl r. RNA. 2014 Oct;20(10):1532-8. doi: 10.1261/rna.045203.114. Epub 2014 Aug 11. RNA. 2014. PMID: 25114291 Free PMC article.

6

Evolutionary diversification of protein-protein interactions by interface add-ons.

Plach MG, Semmelmann F, Busch F, Busch M, Heizinger L, Wysocki VH, Merkl R, Sterner R. Plach MG, et al. Among authors: merkl r. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8333-E8342. doi: 10.1073/pnas.1707335114. Epub 2017 Sep 18. Proc Natl Acad Sci U S A. 2017. PMID: 28923934 Free PMC article.

7

Turning catalytically inactive human Argonaute proteins into active slicer enzymes.

Hauptmann J, Dueck A, Harlander S, Pfaff J, Merkl R, Meister G. Hauptmann J, et al. Among authors: merkl r. Nat Struct Mol Biol. 2013 Jul;20(7):814-7. doi: 10.1038/nsmb.2577. Epub 2013 May 12. Nat Struct Mol Biol. 2013. PMID: 23665583

8

A Fold-Independent Interface Residue Is Crucial for Complex Formation and Allosteric Signaling in Class I Glutamine Amidotransferases.

Semmelmann F, Hupfeld E, Heizinger L, Merkl R, Sterner R. Semmelmann F, et al. Among authors: merkl r. Biochemistry. 2019 Jun 4;58(22):2584-2588. doi: 10.1021/acs.biochem.9b00286. Epub 2019 May 23. Biochemistry. 2019. PMID: 31117390

9

The NHL domain of BRAT is an RNA-binding domain that directly contacts the hunchback mRNA for regulation.

Loedige I, Stotz M, Qamar S, Kramer K, Hennig J, Schubert T, Löffler P, Längst G, Merkl R, Urlaub H, Meister G. Loedige I, et al. Among authors: merkl r. Genes Dev. 2014 Apr 1;28(7):749-64. doi: 10.1101/gad.236513.113. Genes Dev. 2014. PMID: 24696456 Free PMC article.

10

Assessing in silico the recruitment and functional spectrum of bacterial enzymes from secondary metabolism.

Veprinskiy V, Heizinger L, Plach MG, Merkl R. Veprinskiy V, et al. Among authors: merkl r. BMC Evol Biol. 2017 Jan 26;17(1):36. doi: 10.1186/s12862-017-0886-2. BMC Evol Biol. 2017. PMID: 28125959 Free PMC article.

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