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Are New Alzheimer Drugs Better Than Older Drugs?
Molchan S, Fugh-Berman A. Molchan S, et al. JAMA Intern Med. 2023 Jul 31. doi: 10.1001/jamainternmed.2023.3061. Online ahead of print. JAMA Intern Med. 2023. PMID: 37523164
Prevalence and Clinical Implications of a β-Amyloid-Negative, Tau-Positive Cerebrospinal Fluid Biomarker Profile in Alzheimer Disease.
Erickson P, Simrén J, Brum WS, Ennis GE, Kollmorgen G, Suridjan I, Langhough R, Jonaitis EM, Van Hulle CA, Betthauser TJ, Carlsson CM, Asthana S, Ashton NJ, Johnson SC, Shaw LM, Blennow K, Andreasson U, Bendlin BB, Zetterberg H; ADNI Cohort. Erickson P, et al. JAMA Neurol. 2023 Jul 31;80(9):969-79. doi: 10.1001/jamaneurol.2023.2338. Online ahead of print. JAMA Neurol. 2023. PMID: 37523162 Free PMC article.
Amyloid-associated increases in soluble tau relate to tau aggregation rates and cognitive decline in early Alzheimer's disease.
Pichet Binette A, Franzmeier N, Spotorno N, Ewers M, Brendel M, Biel D; Alzheimer’s Disease Neuroimaging Initiative; Strandberg O, Janelidze S, Palmqvist S, Mattsson-Carlgren N, Smith R, Stomrud E, Ossenkoppele R, Hansson O. Pichet Binette A, et al. Nat Commun. 2022 Nov 4;13(1):6635. doi: 10.1038/s41467-022-34129-4. Nat Commun. 2022. PMID: 36333294 Free PMC article.
Comprehensive analysis of epigenetic clocks reveals associations between disproportionate biological ageing and hippocampal volume.
Milicic L, Vacher M, Porter T, Doré V, Burnham SC, Bourgeat P, Shishegar R, Doecke J, Armstrong NJ, Tankard R, Maruff P, Masters CL, Rowe CC, Villemagne VL, Laws SM; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Australian Imaging Biomarkers and Lifestyle (AIBL) Study. Milicic L, et al. Geroscience. 2022 Jun;44(3):1807-1823. doi: 10.1007/s11357-022-00558-8. Epub 2022 Apr 21. Geroscience. 2022. PMID: 35445885 Free PMC article.
159 results