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Chorioretinal thinning in chronic kidney disease links to inflammation and endothelial dysfunction.
Balmforth C, van Bragt JJ, Ruijs T, Cameron JR, Kimmitt R, Moorhouse R, Czopek A, Hu MK, Gallacher PJ, Dear JW, Borooah S, MacIntyre IM, Pearson TM, Willox L, Talwar D, Tafflet M, Roubeix C, Sennlaub F, Chandran S, Dhillon B, Webb DJ, Dhaun N. Balmforth C, et al. Among authors: moorhouse r. JCI Insight. 2016 Dec 8;1(20):e89173. doi: 10.1172/jci.insight.89173. JCI Insight. 2016. PMID: 27942587 Free PMC article.
Therapeutic potential of endothelin receptor antagonism in kidney disease.
Czopek A, Moorhouse R, Webb DJ, Dhaun N. Czopek A, et al. Among authors: moorhouse r. Am J Physiol Regul Integr Comp Physiol. 2016 Mar 1;310(5):R388-97. doi: 10.1152/ajpregu.00478.2015. Epub 2015 Dec 23. Am J Physiol Regul Integr Comp Physiol. 2016. PMID: 26702154 Free article. Review.
Smooth Muscle Endothelin B Receptors Regulate Blood Pressure but Not Vascular Function or Neointimal Remodeling.
Miller E, Czopek A, Duthie KM, Kirkby NS, van de Putte EE, Christen S, Kimmitt RA, Moorhouse R, Castellan RF, Kotelevtsev YV, Kuc RE, Davenport AP, Dhaun N, Webb DJ, Hadoke PW. Miller E, et al. Among authors: moorhouse r. Hypertension. 2017 Feb;69(2):275-285. doi: 10.1161/HYPERTENSIONAHA.115.07031. Epub 2016 Dec 27. Hypertension. 2017. PMID: 28028193 Free PMC article.
First-in-Man Demonstration of Direct Endothelin-Mediated Natriuresis and Diuresis.
Hunter RW, Moorhouse R, Farrah TE, MacIntyre IM, Asai T, Gallacher PJ, Kerr D, Melville V, Czopek A, Morrison EE, Ivy JR, Dear JW, Bailey MA, Goddard J, Webb DJ, Dhaun N. Hunter RW, et al. Among authors: moorhouse r. Hypertension. 2017 Jul;70(1):192-200. doi: 10.1161/HYPERTENSIONAHA.116.08832. Epub 2017 May 15. Hypertension. 2017. PMID: 28507171 Free PMC article. Clinical Trial.
A novel role for myeloid endothelin-B receptors in hypertension.
Czopek A, Moorhouse R, Guyonnet L, Farrah T, Lenoir O, Owen E, van Bragt J, Costello HM, Menolascina F, Baudrie V, Webb DJ, Kluth DC, Bailey MA, Tharaux PL, Dhaun N. Czopek A, et al. Among authors: moorhouse r. Eur Heart J. 2019 Mar 1;40(9):768-784. doi: 10.1093/eurheartj/ehy881. Eur Heart J. 2019. PMID: 30657897 Free PMC article.
36 results