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Activation and self-inactivation mechanisms of the cyclic oligoadenylate-dependent CRISPR ribonuclease Csm6.
Nat Commun. 2020 Mar 27;11(1):1596. doi: 10.1038/s41467-020-15334-5.
Nat Commun. 2020.
PMID: 32221291
Free PMC article.
Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease.
Anders C, Niewoehner O, Duerst A, Jinek M.
Anders C, et al. Among authors: niewoehner o.
Nature. 2014 Sep 25;513(7519):569-73. doi: 10.1038/nature13579. Epub 2014 Jul 27.
Nature. 2014.
PMID: 25079318
Free PMC article.
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Structural basis for the endoribonuclease activity of the type III-A CRISPR-associated protein Csm6.
Niewoehner O, Jinek M.
Niewoehner O, et al.
RNA. 2016 Mar;22(3):318-29. doi: 10.1261/rna.054098.115. Epub 2016 Jan 13.
RNA. 2016.
PMID: 26763118
Free PMC article.
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Type III CRISPR-Cas systems produce cyclic oligoadenylate second messengers.
Niewoehner O, Garcia-Doval C, Rostøl JT, Berk C, Schwede F, Bigler L, Hall J, Marraffini LA, Jinek M.
Niewoehner O, et al.
Nature. 2017 Aug 31;548(7669):543-548. doi: 10.1038/nature23467. Epub 2017 Jul 19.
Nature. 2017.
PMID: 28722012
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Specialized Weaponry: How a Type III-A CRISPR-Cas System Excels at Combating Phages.
Niewoehner O, Jinek M.
Niewoehner O, et al.
Cell Host Microbe. 2017 Sep 13;22(3):258-259. doi: 10.1016/j.chom.2017.08.019.
Cell Host Microbe. 2017.
PMID: 28910631
Free article.
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Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases.
Niewoehner O, Jinek M, Doudna JA.
Niewoehner O, et al.
Nucleic Acids Res. 2014 Jan;42(2):1341-53. doi: 10.1093/nar/gkt922. Epub 2013 Oct 22.
Nucleic Acids Res. 2014.
PMID: 24150936
Free PMC article.
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In Vitro Reconstitution and Crystallization of Cas9 Endonuclease Bound to a Guide RNA and a DNA Target.
Anders C, Niewoehner O, Jinek M.
Anders C, et al. Among authors: niewoehner o.
Methods Enzymol. 2015;558:515-537. doi: 10.1016/bs.mie.2015.02.008. Epub 2015 Mar 12.
Methods Enzymol. 2015.
PMID: 26068752
Free PMC article.
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Identification of the HECT E3 ligase UBR5 as a regulator of MYC degradation using a CRISPR/Cas9 screen.
Schukur L, Zimmermann T, Niewoehner O, Kerr G, Gleim S, Bauer-Probst B, Knapp B, Galli GG, Liang X, Mendiola A, Reece-Hoyes J, Rapti M, Barbosa I, Reschke M, Radimerski T, Thoma CR.
Schukur L, et al. Among authors: niewoehner o.
Sci Rep. 2020 Nov 18;10(1):20044. doi: 10.1038/s41598-020-76960-z.
Sci Rep. 2020.
PMID: 33208877
Free PMC article.
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