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A spatiotemporal Notch interaction map from plasma membrane to nucleus.
Martin AP, Bradshaw GA, Eisert RJ, Egan ED, Tveriakhina L, Rogers JM, Dates AN, Scanavachi G, Aster JC, Kirchhausen T, Kalocsay M, Blacklow SC. Martin AP, et al. Sci Signal. 2023 Aug;16(796):eadg6474. doi: 10.1126/scisignal.adg6474. Epub 2023 Aug 1. Sci Signal. 2023. PMID: 37527352 Free PMC article.
Structure-based design of a SARS-CoV-2 Omicron-specific inhibitor.
Yang K, Wang C, Kreutzberger AJB, White KI, Pfuetzner RA, Esquivies L, Kirchhausen T, Brunger AT. Yang K, et al. Proc Natl Acad Sci U S A. 2023 Mar 28;120(13):e2300360120. doi: 10.1073/pnas.2300360120. Epub 2023 Mar 20. Proc Natl Acad Sci U S A. 2023. PMID: 36940324 Free PMC article.
The beauty of simplicity in membrane biology.
Stachowiak JC, Kirchhausen T. Stachowiak JC, et al. Nat Cell Biol. 2022 Dec;24(12):1682-1685. doi: 10.1038/s41556-022-01015-6. Nat Cell Biol. 2022. PMID: 36266490 Free PMC article.
Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the prehairpin intermediate of the spike protein.
Yang K, Wang C, Kreutzberger AJB, Ojha R, Kuivanen S, Couoh-Cardel S, Muratcioglu S, Eisen TJ, White KI, Held RG, Subramanian S, Marcus K, Pfuetzner RA, Esquivies L, Doyle CA, Kuriyan J, Vapalahti O, Balistreri G, Kirchhausen T, Brunger AT. Yang K, et al. Proc Natl Acad Sci U S A. 2022 Oct 4;119(40):e2210990119. doi: 10.1073/pnas.2210990119. Epub 2022 Sep 19. Proc Natl Acad Sci U S A. 2022. PMID: 36122200 Free PMC article.
28 results