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Timed inhibition of CDC7 increases CRISPR-Cas9 mediated templated repair.
Wienert B, Nguyen DN, Guenther A, Feng SJ, Locke MN, Wyman SK, Shin J, Kazane KR, Gregory GL, Carter MAM, Wright F, Conklin BR, Marson A, Richardson CD, Corn JE. Wienert B, et al. Among authors: richardson cd. Nat Commun. 2020 Apr 30;11(1):2109. doi: 10.1038/s41467-020-15845-1. Nat Commun. 2020. PMID: 32355159 Free PMC article.
Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq.
Wienert B, Wyman SK, Richardson CD, Yeh CD, Akcakaya P, Porritt MJ, Morlock M, Vu JT, Kazane KR, Watry HL, Judge LM, Conklin BR, Maresca M, Corn JE. Wienert B, et al. Among authors: richardson cd. Science. 2019 Apr 19;364(6437):286-289. doi: 10.1126/science.aav9023. Epub 2019 Apr 18. Science. 2019. PMID: 31000663 Free PMC article.
135 results