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Antibody elicited against the gp41 N-heptad repeat (NHR) coiled-coil can neutralize HIV-1 with modest potency but non-neutralizing antibodies also bind to NHR mimetics.
Nelson JD, Kinkead H, Brunel FM, Leaman D, Jensen R, Louis JM, Maruyama T, Bewley CA, Bowdish K, Clore GM, Dawson PE, Frederickson S, Mage RG, Richman DD, Burton DR, Zwick MB. Nelson JD, et al. Among authors: richman dd. Virology. 2008 Jul 20;377(1):170-83. doi: 10.1016/j.virol.2008.04.005. Epub 2008 May 21. Virology. 2008. PMID: 18499210 Free PMC article.
Simian immunodeficiency virus engrafted with human immunodeficiency virus type 1 (HIV-1)-specific epitopes: replication, neutralization, and survey of HIV-1-positive plasma.
Yuste E, Sanford HB, Carmody J, Bixby J, Little S, Zwick MB, Greenough T, Burton DR, Richman DD, Desrosiers RC, Johnson WE. Yuste E, et al. Among authors: richman dd. J Virol. 2006 Mar;80(6):3030-41. doi: 10.1128/JVI.80.6.3030-3041.2006. J Virol. 2006. PMID: 16501112 Free PMC article.
Lack of neutralizing antibody response to HIV-1 predisposes to superinfection.
Smith DM, Strain MC, Frost SD, Pillai SK, Wong JK, Wrin T, Liu Y, Petropolous CJ, Daar ES, Little SJ, Richman DD. Smith DM, et al. Among authors: richman dd. Virology. 2006 Nov 10;355(1):1-5. doi: 10.1016/j.virol.2006.08.009. Epub 2006 Sep 7. Virology. 2006. PMID: 16962152 Free article.
IDEPI: rapid prediction of HIV-1 antibody epitopes and other phenotypic features from sequence data using a flexible machine learning platform.
Hepler NL, Scheffler K, Weaver S, Murrell B, Richman DD, Burton DR, Poignard P, Smith DM, Kosakovsky Pond SL. Hepler NL, et al. Among authors: richman dd. PLoS Comput Biol. 2014 Sep 25;10(9):e1003842. doi: 10.1371/journal.pcbi.1003842. eCollection 2014 Sep. PLoS Comput Biol. 2014. PMID: 25254639 Free PMC article.
Genetic composition of human immunodeficiency virus type 1 in cerebrospinal fluid and blood without treatment and during failing antiretroviral therapy.
Strain MC, Letendre S, Pillai SK, Russell T, Ignacio CC, Günthard HF, Good B, Smith DM, Wolinsky SM, Furtado M, Marquie-Beck J, Durelle J, Grant I, Richman DD, Marcotte T, McCutchan JA, Ellis RJ, Wong JK. Strain MC, et al. Among authors: richman dd. J Virol. 2005 Feb;79(3):1772-88. doi: 10.1128/JVI.79.3.1772-1788.2005. J Virol. 2005. PMID: 15650202 Free PMC article.
553 results