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NCX1 represents an ionic Na+ sensing mechanism in macrophages.
Neubert P, Homann A, Wendelborn D, Bär AL, Krampert L, Trum M, Schröder A, Ebner S, Weichselbaum A, Schatz V, Linz P, Veelken R, Schulte-Schrepping J, Aschenbrenner AC, Quast T, Kurts C, Geisberger S, Kunzelmann K, Hammer K, Binger KJ, Titze J, Müller DN, Kolanus W, Schultze JL, Wagner S, Jantsch J. Neubert P, et al. Among authors: trum m. PLoS Biol. 2020 Jun 22;18(6):e3000722. doi: 10.1371/journal.pbio.3000722. eCollection 2020 Jun. PLoS Biol. 2020. PMID: 32569301 Free PMC article.
Empagliflozin reduces Ca/calmodulin-dependent kinase II activity in isolated ventricular cardiomyocytes.
Mustroph J, Wagemann O, Lücht CM, Trum M, Hammer KP, Sag CM, Lebek S, Tarnowski D, Reinders J, Perbellini F, Terracciano C, Schmid C, Schopka S, Hilker M, Zausig Y, Pabel S, Sossalla ST, Schweda F, Maier LS, Wagner S. Mustroph J, et al. Among authors: trum m. ESC Heart Fail. 2018 Aug;5(4):642-648. doi: 10.1002/ehf2.12336. ESC Heart Fail. 2018. PMID: 30117720 Free PMC article.
Empagliflozin Inhibits Cardiac Late Sodium Current by Ca/Calmodulin-Dependent Kinase II.
Mustroph J, Baier MJ, Pabel S, Stehle T, Trum M, Provaznik Z, Mohler PJ, Musa H, Hund TJ, Sossalla S, Maier LS, Wagner S. Mustroph J, et al. Among authors: trum m. Circulation. 2022 Oct 18;146(16):1259-1261. doi: 10.1161/CIRCULATIONAHA.122.057364. Epub 2022 Oct 17. Circulation. 2022. PMID: 36251785 Free PMC article. No abstract available.
Detrimental proarrhythmogenic interaction of Ca2+/calmodulin-dependent protein kinase II and NaV1.8 in heart failure.
Bengel P, Dybkova N, Tirilomis P, Ahmad S, Hartmann N, A Mohamed B, Krekeler MC, Maurer W, Pabel S, Trum M, Mustroph J, Gummert J, Milting H, Wagner S, Ljubojevic-Holzer S, Toischer K, Maier LS, Hasenfuss G, Streckfuss-Bömeke K, Sossalla S. Bengel P, et al. Among authors: trum m. Nat Commun. 2021 Nov 15;12(1):6586. doi: 10.1038/s41467-021-26690-1. Nat Commun. 2021. PMID: 34782600 Free PMC article.
16 results