Wälti MA - Search Results

1

Probing the mechanism of inhibition of amyloid-β(1-42)-induced neurotoxicity by the chaperonin GroEL.

Wälti MA, Steiner J, Meng F, Chung HS, Louis JM, Ghirlando R, Tugarinov V, Nath A, Clore GM. Wälti MA, et al. Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):E11924-E11932. doi: 10.1073/pnas.1817477115. Epub 2018 Dec 3. Proc Natl Acad Sci U S A. 2018. PMID: 30509980 Free PMC article.

2

Atomic-resolution structure of a disease-relevant Aβ(1-42) amyloid fibril.

Wälti MA, Ravotti F, Arai H, Glabe CG, Wall JS, Böckmann A, Güntert P, Meier BH, Riek R. Wälti MA, et al. Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):E4976-84. doi: 10.1073/pnas.1600749113. Epub 2016 Jul 28. Proc Natl Acad Sci U S A. 2016. PMID: 27469165 Free PMC article.

3

Long Distance Measurements up to 160 Å in the GroEL Tetradecamer Using Q-Band DEER EPR Spectroscopy.

Schmidt T, Wälti MA, Baber JL, Hustedt EJ, Clore GM. Schmidt T, et al. Among authors: walti ma. Angew Chem Int Ed Engl. 2016 Dec 19;55(51):15905-15909. doi: 10.1002/anie.201609617. Epub 2016 Nov 17. Angew Chem Int Ed Engl. 2016. PMID: 27860003 Free PMC article.

4

Chaperonin GroEL accelerates protofibril formation and decorates fibrils of the Het-s prion protein.

Wälti MA, Schmidt T, Murray DT, Wang H, Hinshaw JE, Clore GM. Wälti MA, et al. Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):9104-9109. doi: 10.1073/pnas.1711645114. Epub 2017 Aug 7. Proc Natl Acad Sci U S A. 2017. PMID: 28784759 Free PMC article.

5

Disassembly/reassembly strategy for the production of highly pure GroEL, a tetradecameric supramolecular machine, suitable for quantitative NMR, EPR and mutational studies.

Wälti MA, Clore GM. Wälti MA, et al. Protein Expr Purif. 2018 Feb;142:8-15. doi: 10.1016/j.pep.2017.09.010. Epub 2017 Sep 22. Protein Expr Purif. 2018. PMID: 28951283 Free PMC article.

6

Extensive Sampling of the Cavity of the GroEL Nanomachine by Protein Substrates Probed by Paramagnetic Relaxation Enhancement.

Wälti MA, Libich DS, Clore GM. Wälti MA, et al. J Phys Chem Lett. 2018 Jun 21;9(12):3368-3371. doi: 10.1021/acs.jpclett.8b01586. Epub 2018 Jun 7. J Phys Chem Lett. 2018. PMID: 29869885 Free PMC article.

7

A weakened interface in the P182L variant of HSP27 associated with severe Charcot-Marie-Tooth neuropathy causes aberrant binding to interacting proteins.

Alderson TR, Adriaenssens E, Asselbergh B, Pritišanac I, Van Lent J, Gastall HY, Wälti MA, Louis JM, Timmerman V, Baldwin AJ, Lp Benesch J. Alderson TR, et al. Among authors: walti ma. EMBO J. 2021 Apr 15;40(8):e103811. doi: 10.15252/embj.2019103811. Epub 2021 Mar 1. EMBO J. 2021. PMID: 33644875 Free PMC article.

8

Probing the Interaction of Huntingtin Exon-1 Polypeptides with the Chaperonin Nanomachine GroEL.

Wälti MA, Kotler SA, Clore GM. Wälti MA, et al. Chembiochem. 2021 Jun 2;22(11):1985-1991. doi: 10.1002/cbic.202100055. Epub 2021 Apr 7. Chembiochem. 2021. PMID: 33644966 Free PMC article.

9

Visualization of Sparsely-populated Lower-order Oligomeric States of Human Mitochondrial Hsp60 by Cryo-electron Microscopy.

Wälti MA, Canagarajah B, Schwieters CD, Clore GM. Wälti MA, et al. J Mol Biol. 2021 Dec 3;433(24):167322. doi: 10.1016/j.jmb.2021.167322. Epub 2021 Oct 21. J Mol Biol. 2021. PMID: 34688687 Free PMC article.

10

Solid-state NMR sequential assignment of an Amyloid-β(1-42) fibril polymorph.

Ravotti F, Wälti MA, Güntert P, Riek R, Böckmann A, Meier BH. Ravotti F, et al. Among authors: walti ma. Biomol NMR Assign. 2016 Oct;10(2):269-76. doi: 10.1007/s12104-016-9682-y. Epub 2016 May 10. Biomol NMR Assign. 2016. PMID: 27165577

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