Yu L - Search Results

1

NMR-driven discovery of benzoylanthranilic acid inhibitors of far upstream element binding protein binding to the human oncogene c-myc promoter.

Huth JR, Yu L, Collins I, Mack J, Mendoza R, Isaac B, Braddock DT, Muchmore SW, Comess KM, Fesik SW, Clore GM, Levens D, Hajduk PJ. Huth JR, et al. Among authors: yu l. J Med Chem. 2004 Sep 23;47(20):4851-7. doi: 10.1021/jm0497803. J Med Chem. 2004. PMID: 15369388

2

Discovery of a novel small molecule binding site of human survivin.

Wendt MD, Sun C, Kunzer A, Sauer D, Sarris K, Hoff E, Yu L, Nettesheim DG, Chen J, Jin S, Comess KM, Fan Y, Anderson SN, Isaac B, Olejniczak ET, Hajduk PJ, Rosenberg SH, Elmore SW. Wendt MD, et al. Among authors: yu l. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3122-9. doi: 10.1016/j.bmcl.2007.03.042. Epub 2007 Mar 16. Bioorg Med Chem Lett. 2007. PMID: 17391963

3

Discovery of aminoglycoside mimetics by NMR-based screening of Escherichia coli A-site RNA.

Yu L, Oost TK, Schkeryantz JM, Yang J, Janowick D, Fesik SW. Yu L, et al. J Am Chem Soc. 2003 Apr 16;125(15):4444-50. doi: 10.1021/ja021354o. J Am Chem Soc. 2003. PMID: 12683814

4

Structure of the N-terminal RNA-binding domain of the SARS CoV nucleocapsid protein.

Huang Q, Yu L, Petros AM, Gunasekera A, Liu Z, Xu N, Hajduk P, Mack J, Fesik SW, Olejniczak ET. Huang Q, et al. Among authors: yu l. Biochemistry. 2004 May 25;43(20):6059-63. doi: 10.1021/bi036155b. Biochemistry. 2004. PMID: 15147189

5

Structural studies of Bcl-xL/ligand complexes using 19F NMR.

Yu L, Hajduk PJ, Mack J, Olejniczak ET. Yu L, et al. J Biomol NMR. 2006 Apr;34(4):221-7. doi: 10.1007/s10858-006-0005-y. J Biomol NMR. 2006. PMID: 16645812

6

From bacterial genomes to novel antibacterial agents: discovery, characterization, and antibacterial activity of compounds that bind to HI0065 (YjeE) from Haemophilus influenzae.

Lerner CG, Hajduk PJ, Wagner R, Wagenaar FL, Woodall C, Gu YG, Searle XB, Florjancic AS, Zhang T, Clark RF, Cooper CS, Mack JC, Yu L, Cai M, Betz SF, Chovan LE, McCall JO, Black-Schaefer CL, Kakavas SJ, Schurdak ME, Comess KM, Walter KA, Edalji R, Dorwin SA, Smith RA, Hebert EJ, Harlan JE, Metzger RE, Merta PJ, Baranowski JL, Coen ML, Thornewell SJ, Shivakumar AG, Saiki AY, Soni N, Bui M, Balli DJ, Sanders WJ, Nilius AM, Holzman TF, Fesik SW, Beutel BA. Lerner CG, et al. Among authors: yu l. Chem Biol Drug Des. 2007 Jun;69(6):395-404. doi: 10.1111/j.1747-0285.2007.00521.x. Chem Biol Drug Des. 2007. PMID: 17581233

7

Solution structure and calcium-binding properties of EF-hands 3 and 4 of calsenilin.

Yu L, Sun C, Mendoza R, Wang J, Matayoshi ED, Hebert E, Pereda-Lopez A, Hajduk PJ, Olejniczak ET. Yu L, et al. Protein Sci. 2007 Nov;16(11):2502-9. doi: 10.1110/ps.072928007. Protein Sci. 2007. PMID: 17962406 Free PMC article.

8

Solution structure and function of an essential CMP kinase of Streptococcus pneumoniae.

Yu L, Mack J, Hajduk PJ, Kakavas SJ, Saiki AY, Lerner CG, Olejniczak ET. Yu L, et al. Protein Sci. 2003 Nov;12(11):2613-21. doi: 10.1110/ps.03256803. Protein Sci. 2003. PMID: 14573872 Free PMC article.

9

NMR studies of the FK506 binding protein bound to a spin-labeled ascomycin analog.

Yu L, Meadows RP, Wagner R, Fesik SW. Yu L, et al. J Magn Reson B. 1994 May;104(1):77-80. doi: 10.1006/jmrb.1994.1056. J Magn Reson B. 1994. PMID: 7517786 No abstract available.

10

pH titration of the histidine residues of cyclophilin and FK506 binding protein in the absence and presence of immunosuppressant ligands.

Yu L, Fesik SW. Yu L, et al. Biochim Biophys Acta. 1994 Nov 16;1209(1):24-32. doi: 10.1016/0167-4838(94)90132-5. Biochim Biophys Acta. 1994. PMID: 7524680

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