Bisacchi GS - Search Results

1

Molecular determinants of AcrB-mediated bacterial efflux implications for drug discovery.

Manchester JI, Buurman ET, Bisacchi GS, McLaughlin RE. Manchester JI, et al. Among authors: bisacchi gs. J Med Chem. 2012 Mar 22;55(6):2532-7. doi: 10.1021/jm201275d. Epub 2012 Jan 27. J Med Chem. 2012. PMID: 22224562 No abstract available.

2

A New-Class Antibacterial-Almost. Lessons in Drug Discovery and Development: A Critical Analysis of More than 50 Years of Effort toward ATPase Inhibitors of DNA Gyrase and Topoisomerase IV.

Bisacchi GS, Manchester JI. Bisacchi GS, et al. ACS Infect Dis. 2015 Jan 9;1(1):4-41. doi: 10.1021/id500013t. Epub 2014 Dec 23. ACS Infect Dis. 2015. PMID: 27620144

3

Origins of the Quinolone Class of Antibacterials: An Expanded "Discovery Story".

Bisacchi GS. Bisacchi GS. J Med Chem. 2015 Jun 25;58(12):4874-82. doi: 10.1021/jm501881c. Epub 2015 Mar 12. J Med Chem. 2015. PMID: 25738967 Review.

4

A "Double-Edged" Scaffold: Antitumor Power within the Antibacterial Quinolone.

Bisacchi GS, Hale MR. Bisacchi GS, et al. Curr Med Chem. 2016;23(6):520-77. doi: 10.2174/0929867323666151223095839. Curr Med Chem. 2016. PMID: 26695512 Free PMC article. Review.

5

Phenylimidazoles as potent and selective inhibitors of coagulation factor XIa with in vivo antithrombotic activity.

Hangeland JJ, Friends TJ, Rossi KA, Smallheer JM, Wang C, Sun Z, Corte JR, Fang T, Wong PC, Rendina AR, Barbera FA, Bozarth JM, Luettgen JM, Watson CA, Zhang G, Wei A, Ramamurthy V, Morin PE, Bisacchi GS, Subramaniam S, Arunachalam P, Mathur A, Seiffert DA, Wexler RR, Quan ML. Hangeland JJ, et al. Among authors: bisacchi gs. J Med Chem. 2014 Dec 11;57(23):9915-32. doi: 10.1021/jm5010607. Epub 2014 Dec 2. J Med Chem. 2014. PMID: 25405503

6

Discovery of nonbenzamidine factor VIIa inhibitors using a biaryl acid scaffold.

Bolton SA, Sutton JC, Anumula R, Bisacchi GS, Jacobson B, Slusarchyk WA, Treuner UD, Wu SC, Zhao G, Pi Z, Sheriff S, Smirk RA, Bisaha S, Cheney DL, Wei A, Schumacher WA, Hartl KS, Liu E, Zahler R, Seiler SM. Bolton SA, et al. Among authors: bisacchi gs. Bioorg Med Chem Lett. 2013 Sep 15;23(18):5239-43. doi: 10.1016/j.bmcl.2013.06.028. Epub 2013 Jun 20. Bioorg Med Chem Lett. 2013. PMID: 23927973

7

1,2-Benzisothiazol-3-one 1,1-dioxide inhibitors of human mast cell tryptase.

Combrink KD, Gülgeze HB, Meanwell NA, Pearce BC, Zulan P, Bisacchi GS, Roberts DG, Stanley P, Seiler SM. Combrink KD, et al. Among authors: bisacchi gs. J Med Chem. 1998 Nov 19;41(24):4854-60. doi: 10.1021/jm9804580. J Med Chem. 1998. PMID: 9822554

8

Synthesis and SAR of 4-carboxy-2-azetidinone mechanism-based tryptase inhibitors.

Sutton JC, Bolton SA, Hartl KS, Huang MH, Jacobs G, Meng W, Ogletree ML, Pi Z, Schumacher WA, Seiler SM, Slusarchyk WA, Treuner U, Zahler R, Zhao G, Bisacchi GS. Sutton JC, et al. Among authors: bisacchi gs. Bioorg Med Chem Lett. 2002 Nov 4;12(21):3229-33. doi: 10.1016/s0960-894x(02)00688-1. Bioorg Med Chem Lett. 2002. PMID: 12372540

9

Synthesis of potent and highly selective inhibitors of human tryptase.

Slusarchyk WA, Bolton SA, Hartl KS, Huang MH, Jacobs G, Meng W, Ogletree ML, Pi Z, Schumacher WA, Seiler SM, Sutton JC, Treuner U, Zahler R, Zhao G, Bisacchi GS. Slusarchyk WA, et al. Among authors: bisacchi gs. Bioorg Med Chem Lett. 2002 Nov 4;12(21):3235-8. doi: 10.1016/s0960-894x(02)00689-3. Bioorg Med Chem Lett. 2002. PMID: 12372541

10

Synthesis of potent and selective 2-azepanone inhibitors of human tryptase.

Zhao G, Bolton SA, Kwon C, Hartl KS, Seiler SM, Slusarchyk WA, Sutton JC, Bisacchi GS. Zhao G, et al. Among authors: bisacchi gs. Bioorg Med Chem Lett. 2004 Jan 19;14(2):309-12. doi: 10.1016/j.bmcl.2003.11.016. Bioorg Med Chem Lett. 2004. PMID: 14698147

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

25 results

Search Page