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1,015 results

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Page 1
Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism.
Ying H, Kimmelman AC, Lyssiotis CA, Hua S, Chu GC, Fletcher-Sananikone E, Locasale JW, Son J, Zhang H, Coloff JL, Yan H, Wang W, Chen S, Viale A, Zheng H, Paik JH, Lim C, Guimaraes AR, Martin ES, Chang J, Hezel AF, Perry SR, Hu J, Gan B, Xiao Y, Asara JM, Weissleder R, Wang YA, Chin L, Cantley LC, DePinho RA. Ying H, et al. Among authors: weissleder r. Cell. 2012 Apr 27;149(3):656-70. doi: 10.1016/j.cell.2012.01.058. Cell. 2012. PMID: 22541435 Free PMC article.
Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis.
Bachoo RM, Maher EA, Ligon KL, Sharpless NE, Chan SS, You MJ, Tang Y, DeFrances J, Stover E, Weissleder R, Rowitch DH, Louis DN, DePinho RA. Bachoo RM, et al. Among authors: weissleder r. Cancer Cell. 2002 Apr;1(3):269-77. doi: 10.1016/s1535-6108(02)00046-6. Cancer Cell. 2002. PMID: 12086863 Free article.
Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse.
Bardeesy N, Aguirre AJ, Chu GC, Cheng KH, Lopez LV, Hezel AF, Feng B, Brennan C, Weissleder R, Mahmood U, Hanahan D, Redston MS, Chin L, Depinho RA. Bardeesy N, et al. Among authors: weissleder r. Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5947-52. doi: 10.1073/pnas.0601273103. Epub 2006 Apr 3. Proc Natl Acad Sci U S A. 2006. PMID: 16585505 Free PMC article.
The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies.
Ji H, Li D, Chen L, Shimamura T, Kobayashi S, McNamara K, Mahmood U, Mitchell A, Sun Y, Al-Hashem R, Chirieac LR, Padera R, Bronson RT, Kim W, Jänne PA, Shapiro GI, Tenen D, Johnson BE, Weissleder R, Sharpless NE, Wong KK. Ji H, et al. Among authors: weissleder r. Cancer Cell. 2006 Jun;9(6):485-95. doi: 10.1016/j.ccr.2006.04.022. Epub 2006 May 25. Cancer Cell. 2006. PMID: 16730237 Free article.
Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers.
Engelman JA, Chen L, Tan X, Crosby K, Guimaraes AR, Upadhyay R, Maira M, McNamara K, Perera SA, Song Y, Chirieac LR, Kaur R, Lightbown A, Simendinger J, Li T, Padera RF, García-Echeverría C, Weissleder R, Mahmood U, Cantley LC, Wong KK. Engelman JA, et al. Among authors: weissleder r. Nat Med. 2008 Dec;14(12):1351-6. doi: 10.1038/nm.1890. Epub 2008 Nov 30. Nat Med. 2008. PMID: 19029981 Free PMC article.
BRAF activation initiates but does not maintain invasive prostate adenocarcinoma.
Jeong JH, Wang Z, Guimaraes AS, Ouyang X, Figueiredo JL, Ding Z, Jiang S, Guney I, Kang GH, Shin E, Hahn WC, Loda MF, Abate-Shen C, Weissleder R, Chin L. Jeong JH, et al. Among authors: weissleder r. PLoS One. 2008;3(12):e3949. doi: 10.1371/journal.pone.0003949. Epub 2008 Dec 16. PLoS One. 2008. PMID: 19079609 Free PMC article.
Lymphotropic nanoparticle-enhanced magnetic resonance imaging (LNMRI) identifies occult lymph node metastases in prostate cancer patients prior to salvage radiation therapy.
Ross RW, Zietman AL, Xie W, Coen JJ, Dahl DM, Shipley WU, Kaufman DS, Islam T, Guimaraes AR, Weissleder R, Harisinghani M. Ross RW, et al. Among authors: weissleder r. Clin Imaging. 2009 Jul-Aug;33(4):301-5. doi: 10.1016/j.clinimag.2009.01.013. Clin Imaging. 2009. PMID: 19559353 Clinical Trial.
1,015 results