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Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting.
Matsushita H, Vesely MD, Koboldt DC, Rickert CG, Uppaluri R, Magrini VJ, Arthur CD, White JM, Chen YS, Shea LK, Hundal J, Wendl MC, Demeter R, Wylie T, Allison JP, Smyth MJ, Old LJ, Mardis ER, Schreiber RD. Matsushita H, et al. Nature. 2012 Feb 8;482(7385):400-4. doi: 10.1038/nature10755. Nature. 2012. PMID: 22318521 Free PMC article.
Genomic landscape of non-small cell lung cancer in smokers and never-smokers.
Govindan R, Ding L, Griffith M, Subramanian J, Dees ND, Kanchi KL, Maher CA, Fulton R, Fulton L, Wallis J, Chen K, Walker J, McDonald S, Bose R, Ornitz D, Xiong D, You M, Dooling DJ, Watson M, Mardis ER, Wilson RK. Govindan R, et al. Cell. 2012 Sep 14;150(6):1121-34. doi: 10.1016/j.cell.2012.08.024. Cell. 2012. PMID: 22980976 Free PMC article.
Integrated analysis of germline and somatic variants in ovarian cancer.
Kanchi KL, Johnson KJ, Lu C, McLellan MD, Leiserson MD, Wendl MC, Zhang Q, Koboldt DC, Xie M, Kandoth C, McMichael JF, Wyczalkowski MA, Larson DE, Schmidt HK, Miller CA, Fulton RS, Spellman PT, Mardis ER, Druley TE, Graubert TA, Goodfellow PJ, Raphael BJ, Wilson RK, Ding L. Kanchi KL, et al. Among authors: mardis er. Nat Commun. 2014;5:3156. doi: 10.1038/ncomms4156. Nat Commun. 2014. PMID: 24448499 Free PMC article.
A surprising cross-species conservation in the genomic landscape of mouse and human oral cancer identifies a transcriptional signature predicting metastatic disease.
Onken MD, Winkler AE, Kanchi KL, Chalivendra V, Law JH, Rickert CG, Kallogjeri D, Judd NP, Dunn GP, Piccirillo JF, Lewis JS Jr, Mardis ER, Uppaluri R. Onken MD, et al. Among authors: mardis er. Clin Cancer Res. 2014 Jun 1;20(11):2873-84. doi: 10.1158/1078-0432.CCR-14-0205. Epub 2014 Mar 25. Clin Cancer Res. 2014. PMID: 24668645 Free PMC article.
Patterns and functional implications of rare germline variants across 12 cancer types.
Lu C, Xie M, Wendl MC, Wang J, McLellan MD, Leiserson MD, Huang KL, Wyczalkowski MA, Jayasinghe R, Banerjee T, Ning J, Tripathi P, Zhang Q, Niu B, Ye K, Schmidt HK, Fulton RS, McMichael JF, Batra P, Kandoth C, Bharadwaj M, Koboldt DC, Miller CA, Kanchi KL, Eldred JM, Larson DE, Welch JS, You M, Ozenberger BA, Govindan R, Walter MJ, Ellis MJ, Mardis ER, Graubert TA, Dipersio JF, Ley TJ, Wilson RK, Goodfellow PJ, Raphael BJ, Chen F, Johnson KJ, Parvin JD, Ding L. Lu C, et al. Among authors: mardis er. Nat Commun. 2015 Dec 22;6:10086. doi: 10.1038/ncomms10086. Nat Commun. 2015. PMID: 26689913 Free PMC article.
Rare Variation in TET2 Is Associated with Clinically Relevant Prostate Carcinoma in African Americans.
Koboldt DC, Kanchi KL, Gui B, Larson DE, Fulton RS, Isaacs WB, Kraja A, Borecki IB, Jia L, Wilson RK, Mardis ER, Kibel AS. Koboldt DC, et al. Among authors: mardis er. Cancer Epidemiol Biomarkers Prev. 2016 Nov;25(11):1456-1463. doi: 10.1158/1055-9965.EPI-16-0373. Epub 2016 Aug 2. Cancer Epidemiol Biomarkers Prev. 2016. PMID: 27486019 Free PMC article.
Immunogenomics of Hypermutated Glioblastoma: A Patient with Germline POLE Deficiency Treated with Checkpoint Blockade Immunotherapy.
Johanns TM, Miller CA, Dorward IG, Tsien C, Chang E, Perry A, Uppaluri R, Ferguson C, Schmidt RE, Dahiya S, Ansstas G, Mardis ER, Dunn GP. Johanns TM, et al. Among authors: mardis er. Cancer Discov. 2016 Nov;6(11):1230-1236. doi: 10.1158/2159-8290.CD-16-0575. Epub 2016 Sep 28. Cancer Discov. 2016. PMID: 27683556 Free PMC article.
557 results