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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2003 1
2004 1
2005 3
2006 2
2007 1
2008 1
2009 3
2010 3
2011 3
2012 3
2013 4
2014 2
2015 7
2016 7
2024 0

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38 results

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Page 1
Mechanism of arginine sensing by CASTOR1 upstream of mTORC1.
Saxton RA, Chantranupong L, Knockenhauer KE, Schwartz TU, Sabatini DM. Saxton RA, et al. Nature. 2016 Aug 11;536(7615):229-33. doi: 10.1038/nature19079. Epub 2016 Aug 3. Nature. 2016. PMID: 27487210 Free PMC article.
The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway.
Chantranupong L, Scaria SM, Saxton RA, Gygi MP, Shen K, Wyant GA, Wang T, Harper JW, Gygi SP, Sabatini DM. Chantranupong L, et al. Cell. 2016 Mar 24;165(1):153-164. doi: 10.1016/j.cell.2016.02.035. Epub 2016 Mar 10. Cell. 2016. PMID: 26972053 Free PMC article.
High-fat diet enhances stemness and tumorigenicity of intestinal progenitors.
Beyaz S, Mana MD, Roper J, Kedrin D, Saadatpour A, Hong SJ, Bauer-Rowe KE, Xifaras ME, Akkad A, Arias E, Pinello L, Katz Y, Shinagare S, Abu-Remaileh M, Mihaylova MM, Lamming DW, Dogum R, Guo G, Bell GW, Selig M, Nielsen GP, Gupta N, Ferrone CR, Deshpande V, Yuan GC, Orkin SH, Sabatini DM, Yilmaz ÖH. Beyaz S, et al. Nature. 2016 Mar 3;531(7592):53-8. doi: 10.1038/nature17173. Nature. 2016. PMID: 26935695 Free PMC article.
Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma.
Okosun J, Wolfson RL, Wang J, Araf S, Wilkins L, Castellano BM, Escudero-Ibarz L, Al Seraihi AF, Richter J, Bernhart SH, Efeyan A, Iqbal S, Matthews J, Clear A, Guerra-Assunção JA, Bödör C, Quentmeier H, Mansbridge C, Johnson P, Davies A, Strefford JC, Packham G, Barrans S, Jack A, Du MQ, Calaminici M, Lister TA, Auer R, Montoto S, Gribben JG, Siebert R, Chelala C, Zoncu R, Sabatini DM, Fitzgibbon J. Okosun J, et al. Nat Genet. 2016 Feb;48(2):183-8. doi: 10.1038/ng.3473. Epub 2015 Dec 21. Nat Genet. 2016. PMID: 26691987 Free PMC article.
Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway.
Saxton RA, Knockenhauer KE, Wolfson RL, Chantranupong L, Pacold ME, Wang T, Schwartz TU, Sabatini DM. Saxton RA, et al. Science. 2016 Jan 1;351(6268):53-8. doi: 10.1126/science.aad2087. Epub 2015 Nov 19. Science. 2016. PMID: 26586190 Free PMC article.
Sestrin2 is a leucine sensor for the mTORC1 pathway.
Wolfson RL, Chantranupong L, Saxton RA, Shen K, Scaria SM, Cantor JR, Sabatini DM. Wolfson RL, et al. Science. 2016 Jan 1;351(6268):43-8. doi: 10.1126/science.aab2674. Epub 2015 Oct 8. Science. 2016. PMID: 26449471 Free PMC article.
Identification of an oncogenic RAB protein.
Wheeler DB, Zoncu R, Root DE, Sabatini DM, Sawyers CL. Wheeler DB, et al. Science. 2015 Oct 9;350(6257):211-7. doi: 10.1126/science.aaa4903. Epub 2015 Sep 3. Science. 2015. PMID: 26338797 Free PMC article.
Nutrient-sensing mechanisms across evolution.
Chantranupong L, Wolfson RL, Sabatini DM. Chantranupong L, et al. Cell. 2015 Mar 26;161(1):67-83. doi: 10.1016/j.cell.2015.02.041. Cell. 2015. PMID: 25815986 Free PMC article. Review.
Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1.
Wang S, Tsun ZY, Wolfson RL, Shen K, Wyant GA, Plovanich ME, Yuan ED, Jones TD, Chantranupong L, Comb W, Wang T, Bar-Peled L, Zoncu R, Straub C, Kim C, Park J, Sabatini BL, Sabatini DM. Wang S, et al. Science. 2015 Jan 9;347(6218):188-94. doi: 10.1126/science.1257132. Epub 2015 Jan 7. Science. 2015. PMID: 25567906 Free PMC article.
38 results