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163 results

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A tumor microenvironment-activatable nanoplatform with phycocyanin-assisted in-situ nanoagent generation for synergistic treatment of colorectal cancer.
Sun X, Liang X, Wang Y, Ma P, Xiong W, Qian S, Cui Y, Zhang H, Chen X, Tian F, Shi Y, Zheng F, Li L. Sun X, et al. Biomaterials. 2023 Oct;301:122263. doi: 10.1016/j.biomaterials.2023.122263. Epub 2023 Jul 31. Biomaterials. 2023. PMID: 37549506
The in-situ generation of therapeutic agents in targeted lesions is promising for revolutionizing oncotherapy but is limited by the low production efficiency. Given the specific tumor microenvironment (TME) of colorectal cancer (CRC), i.e., mild acidity, overexpressed H(2) …
The in-situ generation of therapeutic agents in targeted lesions is promising for revolutionizing oncotherapy but is limited by the low prod …
Phycocyanin: A Potential Drug for Cancer Treatment.
Jiang L, Wang Y, Yin Q, Liu G, Liu H, Huang Y, Li B. Jiang L, et al. J Cancer. 2017 Sep 20;8(17):3416-3429. doi: 10.7150/jca.21058. eCollection 2017. J Cancer. 2017. PMID: 29151925 Free PMC article. Review.
Phycocyanin exerts anti-cancer activity by blocking tumor cell cell cycle, inducing tumor cell apoptosis and autophagy, thereby phycocyanin can serve as a promising anti-cancer agent. This review discusses the therapeutic use of phycocyanin and …
Phycocyanin exerts anti-cancer activity by blocking tumor cell cell cycle, inducing tumor cell apoptosis and autophagy, …
Phycocyanin Nanoparticle as a Novel Sonosensitizer for Tumor Sonodynamic Therapy of Michigan Cancer Foundation-7 Cells In Vitro.
Cao J, Pan Q, Zheng M, Shen S, Qi X. Cao J, et al. J Nanosci Nanotechnol. 2021 May 1;21(5):3035-3040. doi: 10.1166/jnn.2021.19139. J Nanosci Nanotechnol. 2021. PMID: 33653477
The development of novel sonosensitizers with safety and efficiency is a key problem in anti-tumor sonodynamic therapy. Phycocyanin (PC) has been proved to have the singlet oxygen radicals (ROS) generation ability, and the potential of PC as a novel sonosensitizer h …
The development of novel sonosensitizers with safety and efficiency is a key problem in anti-tumor sonodynamic therapy. Phycocyani …
Noncovalent Indocyanine Green Conjugate of C-Phycocyanin: Preparation and Tumor-Associated Macrophages-Targeted Photothermal Therapeutics.
Wan DH, Ma XY, Lin C, Zhu DH, Li X, Zheng BY, Li J, Ke MR, Huang JD. Wan DH, et al. Bioconjug Chem. 2020 May 20;31(5):1438-1448. doi: 10.1021/acs.bioconjchem.0c00139. Epub 2020 Apr 15. Bioconjug Chem. 2020. PMID: 32255337
In this work, C-phycocyanin (CPC) as a tumor-associated macrophages (TAMs) targeted vehicle was used to fabricate noncovalent ICG conjugate of CPC (ICG@CPC) via self-assembly in aqueous media. ...In vivo results showed that ICG@CPC had significantly improved drug ac …
In this work, C-phycocyanin (CPC) as a tumor-associated macrophages (TAMs) targeted vehicle was used to fabricate noncovalent …
Advances in delivery methods of Arthrospira platensis (spirulina) for enhanced therapeutic outcomes.
ElFar OA, Billa N, Lim HR, Chew KW, Cheah WY, Munawaroh HSH, Balakrishnan D, Show PL. ElFar OA, et al. Bioengineered. 2022 Jun;13(6):14681-14718. doi: 10.1080/21655979.2022.2100863. Bioengineered. 2022. PMID: 35946342 Free PMC article. Review.
Arthrospira platensis (A. platensis) aqueous extract has massive amounts of natural products that can be used as future drugs, such as C-phycocyanin, allophycocyanin, etc. This extract was chosen because of its high adaptability, which reflects its resolute genetic composi …
Arthrospira platensis (A. platensis) aqueous extract has massive amounts of natural products that can be used as future drugs, such as C- …
The In Vitro Anti-Tumor Activity of Phycocyanin against Non-Small Cell Lung Cancer Cells.
Hao S, Yan Y, Li S, Zhao L, Zhang C, Liu L, Wang C. Hao S, et al. Mar Drugs. 2018 May 23;16(6):178. doi: 10.3390/md16060178. Mar Drugs. 2018. PMID: 29882874 Free PMC article.
Phycocyanin, a type of functional food colorant, is shown to have a potent anti-cancer property. ...Our findings demonstrated the anti-neoplastic function of phycocyanin and provided valuable information for the regulation of phycocyanin in NSCLC cells....
Phycocyanin, a type of functional food colorant, is shown to have a potent anti-cancer property. ...Our findings demonstrated the ant …
Phycocyanin from Arthrospira platensis as Potential Anti-Cancer Drug: Review of In Vitro and In Vivo Studies.
Braune S, Krüger-Genge A, Kammerer S, Jung F, Küpper JH. Braune S, et al. Life (Basel). 2021 Jan 27;11(2):91. doi: 10.3390/life11020091. Life (Basel). 2021. PMID: 33513794 Free PMC article. Review.
Of particular importance is an ingredient of Arthrospira: phycocyanin, a blue-red fluorescent, water-soluble and non-toxic biliprotein pigment. ...In the present review, in vitro and in vivo data on the effects of phycocyanin on various tumor cells and on cel …
Of particular importance is an ingredient of Arthrospira: phycocyanin, a blue-red fluorescent, water-soluble and non-toxic biliprotei …
Phycocyanin inhibits pancreatic cancer metastasis via suppressing epithelial-mesenchymal transition and targeting Akt/beta-catenin pathway.
Huang R, Liao G, Gao M, Ou Y. Huang R, et al. Neoplasma. 2021 Oct 14:210609N773. doi: 10.4149/neo_2021_210609N773. Online ahead of print. Neoplasma. 2021. PMID: 34648301
According to our previous research, phycocyanin (PC) could inhibit pancreatic tumor growth obviously. However, little is known about the effects of phycocyanin on pancreatic tumor metastasis. ...BALB/c nude mice were also inoculated subcutaneously with …
According to our previous research, phycocyanin (PC) could inhibit pancreatic tumor growth obviously. However, little is known …
A hybrid biomaterial of biosilica and C-phycocyanin for enhanced photodynamic effect towards tumor cells.
Pu Y, Wei M, Witkowski A, Krzywda M, Wang Y, Li W. Pu Y, et al. Biochem Biophys Res Commun. 2020 Dec 10;533(3):573-579. doi: 10.1016/j.bbrc.2020.09.049. Epub 2020 Sep 25. Biochem Biophys Res Commun. 2020. PMID: 32981676
This work reports the first fabrication of bio-engineered materials by covalently conjugating C-phycocyanin (C-PC), a natural photosensitizer, to biosilica for the PDT of tumor-associated macrophages. ...
This work reports the first fabrication of bio-engineered materials by covalently conjugating C-phycocyanin (C-PC), a natural photose …
Effects of C-Phycocyanin on the representative genes of tumor development in mouse skin exposed to 12-O-tetradecanoyl-phorbol-13-acetate.
Gupta NK, Gupta KP. Gupta NK, et al. Environ Toxicol Pharmacol. 2012 Nov;34(3):941-8. doi: 10.1016/j.etap.2012.08.001. Epub 2012 Aug 18. Environ Toxicol Pharmacol. 2012. PMID: 22986104
This TPA-caused altered expression of genes was prevented in presence of C-Phycocyanin. This prevention by C-Phycocyanin appeared to be dependent on the dose of C-Phycocyanin used. The results are useful for the detailed study on the preventive effect of C- …
This TPA-caused altered expression of genes was prevented in presence of C-Phycocyanin. This prevention by C-Phycocyanin appea …
163 results