Eckstein F - Search Results

1

Structure-function relationship of hammerhead ribozymes as probed by 2'-modifications.

Pieken WA, Olsen DB, Aurup H, Williams DM, Heidenreich O, Benseler F, Eckstein F. Pieken WA, et al. Among authors: eckstein f. Nucleic Acids Symp Ser. 1991;(24):51-3. Nucleic Acids Symp Ser. 1991. PMID: 1841379

2

Oligonucleotide duplexes containing 2'-amino-2'-deoxycytidines: thermal stability and chemical reactivity.

Aurup H, Tuschl T, Benseler F, Ludwig J, Eckstein F. Aurup H, et al. Among authors: eckstein f. Nucleic Acids Res. 1994 Jan 11;22(1):20-4. doi: 10.1093/nar/22.1.20. Nucleic Acids Res. 1994. PMID: 8127651 Free PMC article.

3

Importance of exocyclic base functional groups of central core guanosines for hammerhead ribozyme activity.

Tuschl T, Ng MM, Pieken W, Benseler F, Eckstein F. Tuschl T, et al. Among authors: eckstein f. Biochemistry. 1993 Nov 2;32(43):11658-68. doi: 10.1021/bi00094a023. Biochemistry. 1993. PMID: 8218233

4

Design of hammerhead ribozymes for the inhibition of gene expression ex vivo by exogenous application.

Eckstein F, Aurup H, Benseler F, Heidenreich O, Marschall P, Ng M, Thomson J, Tuschl T. Eckstein F, et al. Nucleic Acids Symp Ser. 1993;(29):115. Nucleic Acids Symp Ser. 1993. PMID: 8247729 No abstract available.

5

High activity and stability of hammerhead ribozymes containing 2'-modified pyrimidine nucleosides and phosphorothioates.

Heidenreich O, Benseler F, Fahrenholz A, Eckstein F. Heidenreich O, et al. Among authors: eckstein f. J Biol Chem. 1994 Jan 21;269(3):2131-8. J Biol Chem. 1994. PMID: 8294467 Free article.

Previous studies had shown that substitution of all pyrimidine nucleosides by their 2'-fluoro analogs led to an 8-fold decrease in catalytic efficiency in the cleavage reaction compared to the unmodified ribozyme (Heidenreich, O., and Eckstein, F. (1992) J. Biol. Ch …

Previous studies had shown that substitution of all pyrimidine nucleosides by their 2'-fluoro analogs led to an 8-fold decrease in catalytic …

6

Chemically modified RNA: approaches and applications.

Heidenreich O, Pieken W, Eckstein F. Heidenreich O, et al. Among authors: eckstein f. FASEB J. 1993 Jan;7(1):90-6. doi: 10.1096/fasebj.7.1.7678566. FASEB J. 1993. PMID: 7678566 Review.

7

Translation of 2'-modified mRNA in vitro and in vivo.

Aurup H, Siebert A, Benseler F, Williams D, Eckstein F. Aurup H, et al. Among authors: eckstein f. Nucleic Acids Res. 1994 Nov 25;22(23):4963-8. doi: 10.1093/nar/22.23.4963. Nucleic Acids Res. 1994. PMID: 7800487 Free PMC article.

8

Hammerhead ribozyme-mediated cleavage of the long terminal repeat RNA of human immunodeficiency virus type 1.

Heidenreich O, Eckstein F. Heidenreich O, et al. Among authors: eckstein f. J Biol Chem. 1992 Jan 25;267(3):1904-9. J Biol Chem. 1992. PMID: 1730726 Free article.

9

Function of specific 2'-hydroxyl groups of guanosines in a hammerhead ribozyme probed by 2' modifications.

Williams DM, Pieken WA, Eckstein F. Williams DM, et al. Among authors: eckstein f. Proc Natl Acad Sci U S A. 1992 Feb 1;89(3):918-21. doi: 10.1073/pnas.89.3.918. Proc Natl Acad Sci U S A. 1992. PMID: 1736306 Free PMC article.

10

Kinetic characterization of ribonuclease-resistant 2'-modified hammerhead ribozymes.

Pieken WA, Olsen DB, Benseler F, Aurup H, Eckstein F. Pieken WA, et al. Among authors: eckstein f. Science. 1991 Jul 19;253(5017):314-7. doi: 10.1126/science.1857967. Science. 1991. PMID: 1857967

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