An isotope labeling strategy for methyl TROSY spectroscopy.
Tugarinov V, Kay LE.
Tugarinov V, et al.
J Biomol NMR. 2004 Feb;28(2):165-72. doi: 10.1023/B:JNMR.0000013824.93994.1f.
J Biomol NMR. 2004.
PMID: 14755160
These enhancements derive from a TROSY effect in which complete cancellation of intra-methyl (1)H-(1)H and (1)H-(13)C dipolar interactions occurs for 50% of the signal in the case of HMQC, so long as the methyl is attached to a molecule tumbling in the macromolecular limit (Tu …
These enhancements derive from a TROSY effect in which complete cancellation of intra-methyl (1)H-(1)H and (1)H-(13)C dipolar interactions o …