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Latent enhancers activated by stimulation in differentiated cells.
Ostuni R, Piccolo V, Barozzi I, Polletti S, Termanini A, Bonifacio S, Curina A, Prosperini E, Ghisletti S, Natoli G. Ostuni R, et al. Among authors: piccolo v. Cell. 2013 Jan 17;152(1-2):157-71. doi: 10.1016/j.cell.2012.12.018. Cell. 2013. PMID: 23332752 Free article.
Transcription of Mammalian cis-Regulatory Elements Is Restrained by Actively Enforced Early Termination.
Austenaa LM, Barozzi I, Simonatto M, Masella S, Della Chiara G, Ghisletti S, Curina A, de Wit E, Bouwman BA, de Pretis S, Piccolo V, Termanini A, Prosperini E, Pelizzola M, de Laat W, Natoli G. Austenaa LM, et al. Among authors: piccolo v. Mol Cell. 2015 Nov 5;60(3):460-74. doi: 10.1016/j.molcel.2015.09.018. Epub 2015 Oct 22. Mol Cell. 2015. PMID: 26593720 Free article.
A first exon termination checkpoint preferentially suppresses extragenic transcription.
Austenaa LMI, Piccolo V, Russo M, Prosperini E, Polletti S, Polizzese D, Ghisletti S, Barozzi I, Diaferia GR, Natoli G. Austenaa LMI, et al. Among authors: piccolo v. Nat Struct Mol Biol. 2021 Apr;28(4):337-346. doi: 10.1038/s41594-021-00572-y. Epub 2021 Mar 25. Nat Struct Mol Biol. 2021. PMID: 33767452 Free PMC article.
Restrictor synergizes with Symplekin and PNUTS to terminate extragenic transcription.
Russo M, Piccolo V, Polizzese D, Prosperini E, Borriero C, Polletti S, Bedin F, Marenda M, Michieletto D, Mandana GM, Rodighiero S, Cuomo A, Natoli G. Russo M, et al. Among authors: piccolo v. Genes Dev. 2023 Dec 26;37(21-24):1017-1040. doi: 10.1101/gad.351057.123. Genes Dev. 2023. PMID: 38092518 Free PMC article.
Tumor-Derived Prostaglandin E2 Promotes p50 NF-κB-Dependent Differentiation of Monocytic MDSCs.
Porta C, Consonni FM, Morlacchi S, Sangaletti S, Bleve A, Totaro MG, Larghi P, Rimoldi M, Tripodo C, Strauss L, Banfi S, Storto M, Pressiani T, Rimassa L, Tartari S, Ippolito A, Doni A, Soldà G, Duga S, Piccolo V, Ostuni R, Natoli G, Bronte V, Balzac F, Turco E, Hirsch E, Colombo MP, Sica A. Porta C, et al. Among authors: piccolo v. Cancer Res. 2020 Jul 1;80(13):2874-2888. doi: 10.1158/0008-5472.CAN-19-2843. Epub 2020 Apr 7. Cancer Res. 2020. PMID: 32265223
224 results